Acoustic trapping: an emerging tool in micro-array technologies

讲座名称：Acoustic trapping: an emerging tool in micro-array technologies

讲座人：田良飞 研究员

讲座时间：4月10日10:30

地点：南校区G420

讲座人介绍：

田良飞研究员，博士毕业于苏黎世联邦理工学院；分别在德国康斯坦茨大学和英国布里斯托大学从事博士后研究工作。2019年11月加入浙江大学生物医学工程与仪器科学学院，任“百人计划”研究员，并担任浙江大学附属妇产科医院及浙江大学滨江研究院兼职教授。近年来，田良飞博士在超声操控技术领域取得了一系列原创性高水平研究成果，并探索了其在生物医学领域中的应用。先后在Nature Chemistry(2)、Nature Communications(3)等国际知名学术期刊发表论文30余篇，申请并授权发明专利8项，孵化一家生物技术企业，相关产品已经进入临床一期的测试。其研究成果先后被包括英国皇家工程协会、英国皇家化学协会和美国物理协会等专业协会会刊在内的近40余家科技媒体报道，在业界引发了广泛的关注。

讲座内容：

Spatial indexing is critical in experiments that require to identify and monitor hundreds to millions of individual microcompartments over a range of timescales and chemical/physical environments. This enables the high-throughput analyses of chemical/biochemical, and cellular processes, and the digital measurements of rare events in a large sample. Systematic arrangement of individual or clusters micro-compartments or cells in 2D micro-arrays provides a miniaturized platform, in which the addressability of the objects in the array can be indexed on the basis of one or more spatial variables. Typically, arrays of micro-compartments or cells with a uniform size have been prepared by microfluidics, microfabrication, printing and by application of electrical or magnetic fields. In this talk, I will present some of our recent work on how to utilize ultrasound to organize liquid droplets, lipid vesicles, and cells in 2D micro-array. I will also discuss the use of micro-array for non-equilibrium chemical sensing, protocellular differentiation, the construction of synthetic “prototissues”, exploration of localized enzyme-directed chemical communication, and design of vesicle-mediated chemical communication pathways in protocell/living cell consortia.

主办单位：生命科学技术学院